经尿道钬激光膀胱肿瘤切除术和膀胱肿瘤电切术治疗表浅层膀胱癌的效果比较

发布于:2021-11-29 11:17:45

龙源期刊网 http://www.qikan.com.cn 经尿道钬激光膀胱肿瘤切除术和膀胱肿瘤电 切术治疗表浅层膀胱癌的效果比较 作者:苏学勇 潘翔 刘永昌 来源:《中国当代医药》2018 年第 11 期 [摘要]目的 探讨经尿道钬激光膀胱肿瘤切除术和膀胱肿瘤电切术治疗表浅层膀胱癌的临床 效果。方法 选取 2012 年 12 月~2017 年 10 月我院收治的 50 例表浅层膀胱癌患者,根据随机 数字表法分为观察组和对照组,每组各 25 例。观察组患者采用经尿道钬激光膀胱肿瘤切除术 治疗,对照组患者采用经尿道膀胱肿瘤电切术治疗。比较两组患者的手术操作用时、术中实际 出血量、留置尿管时长、住院天数、治疗前后炎症因子水*以及并发症发生率。结果 观察组 患者手术操作用时、留置尿管时长、住院天数明显短于对照组,术中实际出血量少于对照组, IL-6、IL-8、TNF-α 以及并发症发生率明显低于对照组,IL-10 水*明显高于对照组,差异均有 统计学意义(P [关键词]钬激光膀胱肿瘤切除术;膀胱肿瘤电切术;表浅层膀胱癌;临床效果 [中图分类号] R694 [文献标识码] A [文章编号] 1674-4721(2018)4(b)-0075-03 Transurethral holmium laser bladder resection and bladder tumor resection for superficial bladder cancer SU Xue-yong PAN Xiang LIU Yong-chang Department of urology,People′s Hospital of Gaoyao District in Zhaoqing City,Guangdong Province,Zhaoqing 526040,China [Abstract]Objective To investigate the clinical effect of transurethral holmium laser bladder tumor resection and bladder tumor resection for superficial bladder cancer.Methods 50 patients with superficial bladder cancer admitted from December 2012 to October 2017 in our hospital were divided into observation group (n=25) and control group according to random number table method.The observation group was treated by transurethral holmium laser bladder tumor resection,while the control group was treated by transurethral resection of bladder tumor.The operation time, intraoperative blood loss,length of indwelling catheter,days of hospitalization,levels of inflammatory cytokines before and after treatment and complication rates were compared between the two groups.Results The operation time,indwelling catheter length,length of hospital stay were shorter than those in control group, intraoperative blood loss was losser than those in the control, IL-6,IL-8,TNF-α and complication rates in observation group were significantly lower than those in control group,and IL-10 level was higher than that in control group,the differences were statistically significant (P 龙源期刊网 http://www.qikan.com.cn [Key words]Holmium laser bladder tumor resection;Bladder tumor resection;Superficial bladder cancer;Clinical effect 表浅层膀胱癌是泌尿外科常见的肿瘤类型,具有较高的发病率及复发率,对患者健康造成 严重影响,若治疗不及时会导致病情恶化,甚至影响患者的日常生活,需要及时采取有效措施 来改善患者预后,提高其生活质量。对表浅层膀胱癌患者进行早期诊断、早期检查以及早期治 疗至关重要,可有效降低发病率、复发率以及死亡率,可保证患者生命安全[1]。临床治疗表 浅层膀胱癌的手术方法主要有钬激光膀胱肿瘤切除术以及膀胱肿瘤电切术,两种方法均具有一 定疗效,可达到延长患者寿命的目的,但膀胱肿瘤电切术所需手术时间较长,难以将肿瘤组织 完整切除,对术后肿瘤病理结果造成影响,在切除直径范围较大肿瘤时会增加出血量,且在肿 瘤表面过多切割还会增加膀胱穿孔的风险,不利于改善患者预后[2]。本研究主要探讨经尿道 钬激光膀胱肿瘤切除术和膀胱肿瘤电切术治疗表浅层膀胱癌的临床效果,现报道如下。 1 资料与方法 1.1 一般资料 随机

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